Drug interactions
Morphine + Motherwort
Severity: Minor
Morphine and Motherwort: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Motherwort is traditionally regarded as a mild sedative herb, and it may add to the central nervous system depression produced by morphine. Drowsiness and impaired alertness could be more pronounced than with morphine alone.
What this interaction means in plain words
Morphine and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive CNS depressant effects; the sedative action of motherwort is theoretical and poorly characterized.
What to do
Ask patients about herbal product use and advise them to avoid driving or hazardous tasks if drowsy. Reduce or stop the herb if excess sedation occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Morphine and Motherwort, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Morphine
- Alvimopan + Morphine Contraindicated
- Isocarboxazid + Morphine Contraindicated
- Morphine + Olanzapine / samidorphan Contraindicated
- Morphine + Phenelzine Contraindicated
- Morphine + Tranylcypromine Contraindicated
- Alfentanil + Morphine Major
Frequently asked questions
Can I take Morphine with Motherwort?
MediHelp rates the interaction as minor. Morphine and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Motherwort is traditionally regarded as a mild sedative herb, and it may add to the central nervous system depression produced by morphine. Drowsiness and impaired alertness could be more pronounced than with morphine alone.
How serious is the interaction between Morphine and Motherwort?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal product use and advise them to avoid driving or hazardous tasks if drowsy. Reduce or stop the herb if excess sedation occurs.
What other medicines interact with Morphine?
MediHelp also lists interactions of Morphine with, for example, Alvimopan, Isocarboxazid, Olanzapine / samidorphan. The full list is on the Morphine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
