Drug interactions
Moxisylyte + Timolol
Severity: Moderate
Moxisylyte and Timolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxisylyte is an alpha-blocking vasodilator, and combining it with timolol may produce additive hypotension. Orthostatic dizziness is the main concern.
What this interaction means in plain words
Moxisylyte and Timolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic effect: alpha-adrenergic blockade-induced vasodilation combined with beta-blocker reduction of cardiac output.
What to do
Monitor blood pressure, including standing readings, when the combination is started. Advise the patient to rise slowly and reduce doses if symptomatic hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
- Atenolol-chlorthalidone + Timolol Major
Frequently asked questions
Can I take Moxisylyte with Timolol?
MediHelp rates the interaction as moderate. Moxisylyte and Timolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Moxisylyte is an alpha-blocking vasodilator, and combining it with timolol may produce additive hypotension. Orthostatic dizziness is the main concern.
How serious is the interaction between Moxisylyte and Timolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, including standing readings, when the combination is started. Advise the patient to rise slowly and reduce doses if symptomatic hypotension occurs.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Timolol page.
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