Drug interactions
Moxisylyte + Tolmetin
Severity: Minor
Moxisylyte and Tolmetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxisylyte is an alpha-blocking vasodilator used for peripheral vascular disorders and erectile dysfunction. NSAIDs reduce prostaglandin-mediated vasodilation and could theoretically blunt its effect, but supporting data are scarce.
What this interaction means in plain words
Moxisylyte and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic antagonism through reduced vasodilatory prostaglandin synthesis.
What to do
No routine action is required. Reassess efficacy if the response to moxisylyte decreases.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Frequently asked questions
Can I take Moxisylyte with Tolmetin?
MediHelp rates the interaction as minor. Moxisylyte and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Moxisylyte is an alpha-blocking vasodilator used for peripheral vascular disorders and erectile dysfunction. NSAIDs reduce prostaglandin-mediated vasodilation and could theoretically blunt its effect, but supporting data are scarce.
How serious is the interaction between Moxisylyte and Tolmetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is required. Reassess efficacy if the response to moxisylyte decreases.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
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