Drug interactions
Mycophenolate + Trastuzumab
Severity: Moderate
Mycophenolate and Trastuzumab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mycophenolate is an immunosuppressant that can cause neutropenia and increases susceptibility to infection. Combined with trastuzumab, which can add to neutropenia when used with cytotoxic therapy, the risk of infection may be greater.
What this interaction means in plain words
Mycophenolate and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive immunosuppression and bone marrow suppression.
What to do
Monitor complete blood counts and for signs of infection. Reduce or hold mycophenolate if significant neutropenia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Trastuzumab
Frequently asked questions
Can I take Mycophenolate with Trastuzumab?
MediHelp rates the interaction as moderate. Mycophenolate and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mycophenolate is an immunosuppressant that can cause neutropenia and increases susceptibility to infection. Combined with trastuzumab, which can add to neutropenia when used with cytotoxic therapy, the risk of infection may be greater.
How serious is the interaction between Mycophenolate and Trastuzumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts and for signs of infection. Reduce or hold mycophenolate if significant neutropenia develops.
What other medicines interact with Trastuzumab?
MediHelp also lists interactions of Trastuzumab with, for example, Daunorubicin, Doxorubicin liposomal, Doxorubicin. The full list is on the Trastuzumab page.
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