Drug interactions
Albuterol + Nebivolol
Severity: Moderate
Albuterol and Nebivolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nebivolol is a highly beta-1 selective blocker, but at higher doses or in susceptible patients it can still blunt the bronchodilating effect of albuterol and may provoke bronchospasm in asthma. Albuterol may also reduce beta-blocker effect on heart rate.
What this interaction means in plain words
Albuterol and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism at beta adrenergic receptors, with loss of cardioselectivity at higher doses.
What to do
Use the lowest nebivolol dose in patients with reactive airway disease and monitor respiratory symptoms and response to albuterol; reassess the need for the beta-blocker if bronchospasm occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Albuterol with Nebivolol?
MediHelp rates the interaction as moderate. Albuterol and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nebivolol is a highly beta-1 selective blocker, but at higher doses or in susceptible patients it can still blunt the bronchodilating effect of albuterol and may provoke bronchospasm in asthma. Albuterol may also reduce beta-blocker effect on heart rate.
How serious is the interaction between Albuterol and Nebivolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest nebivolol dose in patients with reactive airway disease and monitor respiratory symptoms and response to albuterol; reassess the need for the beta-blocker if bronchospasm occurs.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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