Drug interactions
Neomycin po + Vitamin a
Severity: Minor
Neomycin po and Vitamin a: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral neomycin can cause malabsorption of fat and fat-soluble vitamins by disrupting intestinal mucosa and micelle formation. Vitamin A absorption may fall, which matters mainly with prolonged neomycin use.
What this interaction means in plain words
Neomycin po and Vitamin a have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Neomycin-induced impairment of intestinal fat and micelle absorption reduces vitamin A uptake.
What to do
Monitor vitamin A status if oral neomycin is used for a prolonged period and supplement if deficiency develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vitamin a
- Acitretin + Vitamin a Major
- Etretinate + Vitamin a Major
- Isotretinoin + Vitamin a Major
- Palovarotene + Vitamin a Major
- Bexarotene + Vitamin a Moderate
- Minocycline + Vitamin a Moderate
Frequently asked questions
Can I take Neomycin po with Vitamin a?
MediHelp rates the interaction as minor. Neomycin po and Vitamin a have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral neomycin can cause malabsorption of fat and fat-soluble vitamins by disrupting intestinal mucosa and micelle formation. Vitamin A absorption may fall, which matters mainly with prolonged neomycin use.
How serious is the interaction between Neomycin po and Vitamin a?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor vitamin A status if oral neomycin is used for a prolonged period and supplement if deficiency develops.
What other medicines interact with Vitamin a?
MediHelp also lists interactions of Vitamin a with, for example, Acitretin, Etretinate, Isotretinoin. The full list is on the Vitamin a page.
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