Drug interactions
Nettle + Tolmetin
Severity: Minor
Nettle and Tolmetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nettle has been described with both anticoagulant-enhancing and anticoagulant-opposing effects, and the evidence is weak. No reliable clinical interaction with tolmetin has been shown.
What this interaction means in plain words
Nettle and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mechanism not established; nettle may variably affect coagulation.
What to do
No specific action is needed. Counsel patients to report unusual bleeding if they use nettle supplements regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Frequently asked questions
Can I take Nettle with Tolmetin?
MediHelp rates the interaction as minor. Nettle and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nettle has been described with both anticoagulant-enhancing and anticoagulant-opposing effects, and the evidence is weak. No reliable clinical interaction with tolmetin has been shown.
How serious is the interaction between Nettle and Tolmetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed. Counsel patients to report unusual bleeding if they use nettle supplements regularly.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
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