Drug interactions
Nifedipine + Shepherd's purse
Severity: Minor
Nifedipine and Shepherd's purse: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Shepherd's purse has been reported to affect blood pressure, and could in theory oppose or unpredictably alter the effect of nifedipine. Evidence is limited to traditional use and animal data.
What this interaction means in plain words
Nifedipine and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Not established; theoretical pharmacodynamic effect on blood pressure.
What to do
Advise patients to avoid the herb or monitor blood pressure if it is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nifedipine
Frequently asked questions
Can I take Nifedipine with Shepherd's purse?
MediHelp rates the interaction as minor. Nifedipine and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shepherd's purse has been reported to affect blood pressure, and could in theory oppose or unpredictably alter the effect of nifedipine. Evidence is limited to traditional use and animal data.
How serious is the interaction between Nifedipine and Shepherd's purse?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid the herb or monitor blood pressure if it is used.
What other medicines interact with Nifedipine?
MediHelp also lists interactions of Nifedipine with, for example, Amifostine, Amlodipine-benazepril, Apalutamide. The full list is on the Nifedipine page.
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