Drug interactions
Nilotinib + Quercetin
Severity: Minor
Nilotinib and Quercetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quercetin may alter P-glycoprotein activity and in theory affect nilotinib absorption. The clinical effect is uncertain and probably small.
What this interaction means in plain words
Nilotinib and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible modulation of P-glycoprotein and intestinal transport; the mechanism is not firmly established.
What to do
Advise avoiding high-dose quercetin supplements. Monitor response if supplementation continues.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nilotinib
- Amiodarone + Nilotinib Contraindicated
- Arsenic trioxide + Nilotinib Contraindicated
- Disopyramide + Nilotinib Contraindicated
- Dofetilide + Nilotinib Contraindicated
- Dronedarone + Nilotinib Contraindicated
- Droperidol + Nilotinib Contraindicated
Frequently asked questions
Can I take Nilotinib with Quercetin?
MediHelp rates the interaction as minor. Nilotinib and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quercetin may alter P-glycoprotein activity and in theory affect nilotinib absorption. The clinical effect is uncertain and probably small.
How serious is the interaction between Nilotinib and Quercetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding high-dose quercetin supplements. Monitor response if supplementation continues.
What other medicines interact with Nilotinib?
MediHelp also lists interactions of Nilotinib with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Nilotinib page.
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