Drug interactions
Olodaterol inhaled + Prednisolone
Severity: Moderate
Olodaterol inhaled and Prednisolone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can lower serum potassium, and together they may cause hypokalemia, especially at high steroid doses. This can raise the risk of arrhythmias in susceptible patients.
What this interaction means in plain words
Olodaterol inhaled and Prednisolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Beta-2 agonists drive potassium into cells and corticosteroids increase renal potassium excretion, giving additive hypokalemia.
What to do
Check serum potassium in patients on high-dose steroids or other potassium-lowering drugs. Replace potassium as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Prednisolone
- Bcg vaccine live + Prednisolone Contraindicated
- Measles mumps and rubella vaccine live + Prednisolone Contraindicated
- Measles mumps rubella and varicella vaccine live + Prednisolone Contraindicated
- Measles vaccine + Prednisolone Contraindicated
- Mifepristone + Prednisolone Contraindicated
- Prednisolone + Radium-223 dichloride Contraindicated
Frequently asked questions
Can I take Olodaterol inhaled with Prednisolone?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Prednisolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can lower serum potassium, and together they may cause hypokalemia, especially at high steroid doses. This can raise the risk of arrhythmias in susceptible patients.
How serious is the interaction between Olodaterol inhaled and Prednisolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium in patients on high-dose steroids or other potassium-lowering drugs. Replace potassium as needed.
What other medicines interact with Prednisolone?
MediHelp also lists interactions of Prednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Prednisolone page.
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