Drug interactions
Olodaterol inhaled + Pseudoephedrine
Severity: Moderate
Olodaterol inhaled and Pseudoephedrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Concurrent use of a sympathomimetic and a long-acting beta agonist can intensify cardiovascular effects such as tachycardia, palpitations and elevated blood pressure. Patients with cardiac disease are more susceptible.
What this interaction means in plain words
Olodaterol inhaled and Pseudoephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive adrenergic stimulation from beta-2 agonism and indirect sympathomimetic activity.
What to do
Monitor heart rate and blood pressure and ask about palpitations. Avoid pseudoephedrine in patients with significant cardiovascular disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Pseudoephedrine
- Isocarboxazid + Pseudoephedrine Contraindicated
- Phenelzine + Pseudoephedrine Contraindicated
- Pseudoephedrine + Rasagiline Contraindicated
- Pseudoephedrine + Selegiline Contraindicated
- Pseudoephedrine + Selegiline transdermal Contraindicated
- Pseudoephedrine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Olodaterol inhaled with Pseudoephedrine?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Pseudoephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Concurrent use of a sympathomimetic and a long-acting beta agonist can intensify cardiovascular effects such as tachycardia, palpitations and elevated blood pressure. Patients with cardiac disease are more susceptible.
How serious is the interaction between Olodaterol inhaled and Pseudoephedrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure and ask about palpitations. Avoid pseudoephedrine in patients with significant cardiovascular disease.
What other medicines interact with Pseudoephedrine?
MediHelp also lists interactions of Pseudoephedrine with, for example, Isocarboxazid, Phenelzine, Rasagiline. The full list is on the Pseudoephedrine page.
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