Drug interactions
Olodaterol inhaled + Quinine
Severity: Moderate
Olodaterol inhaled and Quinine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinine prolongs the QT interval, and beta2 agonists such as olodaterol can cause hypokalemia and tachycardia. Together they may raise the risk of ventricular arrhythmias, although inhaled systemic exposure to olodaterol is low.
What this interaction means in plain words
Olodaterol inhaled and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation and beta2-agonist cardiovascular effects.
What to do
Monitor ECG and serum potassium in patients with cardiac risk factors. Avoid exceeding the recommended olodaterol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Frequently asked questions
Can I take Olodaterol inhaled with Quinine?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quinine prolongs the QT interval, and beta2 agonists such as olodaterol can cause hypokalemia and tachycardia. Together they may raise the risk of ventricular arrhythmias, although inhaled systemic exposure to olodaterol is low.
How serious is the interaction between Olodaterol inhaled and Quinine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium in patients with cardiac risk factors. Avoid exceeding the recommended olodaterol dose.
What other medicines interact with Quinine?
MediHelp also lists interactions of Quinine with, for example, Arsenic trioxide, Dofetilide, Dronedarone. The full list is on the Quinine page.
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