Drug interactions
Olodaterol inhaled + Sunitinib
Severity: Moderate
Olodaterol inhaled and Sunitinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sunitinib can prolong the QT interval, and beta2 agonists can cause hypokalemia and tachycardia that may add to arrhythmic risk. Systemic exposure to inhaled olodaterol is low, so the risk is modest at usual doses.
What this interaction means in plain words
Olodaterol inhaled and Sunitinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic effects on cardiac repolarization and beta2-mediated hypokalemia.
What to do
Obtain a baseline ECG and monitor potassium and magnesium, correcting abnormalities. Do not exceed the recommended olodaterol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Sunitinib
- Adagrasib + Sunitinib Major
- Amiodarone + Sunitinib Major
- Amisulpride + Sunitinib Major
- Anagrelide + Sunitinib Major
- Apalutamide + Sunitinib Major
- Arsenic trioxide + Sunitinib Major
Frequently asked questions
Can I take Olodaterol inhaled with Sunitinib?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Sunitinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sunitinib can prolong the QT interval, and beta2 agonists can cause hypokalemia and tachycardia that may add to arrhythmic risk. Systemic exposure to inhaled olodaterol is low, so the risk is modest at usual doses.
How serious is the interaction between Olodaterol inhaled and Sunitinib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor potassium and magnesium, correcting abnormalities. Do not exceed the recommended olodaterol dose.
What other medicines interact with Sunitinib?
MediHelp also lists interactions of Sunitinib with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Sunitinib page.
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