Drug interactions
Oxazepam + Scullcap
Severity: Minor
Oxazepam and Scullcap: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Skullcap herbal products are traditionally used as mild sedatives and may add to benzodiazepine drowsiness. Evidence for a clinically important interaction is limited.
What this interaction means in plain words
Oxazepam and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive GABAergic sedation; not well established.
What to do
Advise patients to report increased drowsiness and to avoid driving if affected. Consider stopping the herbal product if sedation is excessive.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxazepam
- Calcium / magnesium / potassium / sodium oxybates + Oxazepam Contraindicated
- Oxazepam + Sodium oxybate Contraindicated
- Alfentanil + Oxazepam Major
- Amobarbital + Oxazepam Major
- Baclofen + Oxazepam Major
- Belladonna and opium + Oxazepam Major
Frequently asked questions
Can I take Oxazepam with Scullcap?
MediHelp rates the interaction as minor. Oxazepam and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Skullcap herbal products are traditionally used as mild sedatives and may add to benzodiazepine drowsiness. Evidence for a clinically important interaction is limited.
How serious is the interaction between Oxazepam and Scullcap?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report increased drowsiness and to avoid driving if affected. Consider stopping the herbal product if sedation is excessive.
What other medicines interact with Oxazepam?
MediHelp also lists interactions of Oxazepam with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Oxazepam page.
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