Drug interactions
Pasireotide + Salbutamol
Severity: Moderate
Pasireotide and Salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pasireotide can prolong the QT interval and cause bradycardia. High-dose salbutamol may add to QT risk via hypokalemia and cardiac stimulation.
What this interaction means in plain words
Pasireotide and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pasireotide belongs to Endocrine; Salbutamol belongs to Respiratory.
Why it happens
Additive effects on cardiac repolarization, with beta-2 mediated hypokalemia.
What to do
Monitor ECG and serum potassium and magnesium, correcting deficits before and during treatment. Avoid excessive salbutamol use.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salbutamol
Other interactions of Pasireotide
- Dronedarone + Pasireotide Contraindicated
- Pasireotide + Pimozide Contraindicated
- Amiodarone + Pasireotide Major
- Amisulpride + Pasireotide Major
- Amitriptyline + Pasireotide Major
- Anagrelide + Pasireotide Major
Frequently asked questions
Can I take Pasireotide with Salbutamol?
MediHelp rates the interaction as moderate. Pasireotide and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pasireotide can prolong the QT interval and cause bradycardia. High-dose salbutamol may add to QT risk via hypokalemia and cardiac stimulation.
How serious is the interaction between Pasireotide and Salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium and magnesium, correcting deficits before and during treatment. Avoid excessive salbutamol use.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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