Drug interactions
Pau d'arco + Tolmetin
Severity: Minor
Pau d'arco and Tolmetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pau d'arco has theoretical anticoagulant activity, and tolmetin inhibits platelet function and can cause gastrointestinal bleeding. Combined use may increase bleeding tendency, though clinical reports are lacking.
What this interaction means in plain words
Pau d'arco and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive effects on hemostasis; the herbal mechanism is not well established.
What to do
Advise patients to avoid the herbal product while taking tolmetin, particularly if they also use anticoagulants. Monitor for bruising or bleeding if used together.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Frequently asked questions
Can I take Pau d'arco with Tolmetin?
MediHelp rates the interaction as minor. Pau d'arco and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pau d'arco has theoretical anticoagulant activity, and tolmetin inhibits platelet function and can cause gastrointestinal bleeding. Combined use may increase bleeding tendency, though clinical reports are lacking.
How serious is the interaction between Pau d'arco and Tolmetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid the herbal product while taking tolmetin, particularly if they also use anticoagulants. Monitor for bruising or bleeding if used together.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
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