Drug interactions
Penicillamine + Peramivir
Severity: Minor
Penicillamine and Peramivir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are renally eliminated and penicillamine can be nephrotoxic. Reduced kidney function could raise peramivir exposure, though a direct pharmacokinetic interaction is not well established.
What this interaction means in plain words
Penicillamine and Peramivir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive renal effects; no established pharmacokinetic mechanism.
What to do
Monitor renal function and adjust peramivir dosing according to creatinine clearance.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Penicillamine
- Gold sodium thiomalate + Penicillamine Major
- Aluminum hydroxide + Penicillamine Moderate
- Calcium carbonate + Penicillamine Moderate
- Calcium + Penicillamine Moderate
- Carbonyl iron + Penicillamine Moderate
- Copper + Penicillamine Moderate
Frequently asked questions
Can I take Penicillamine with Peramivir?
MediHelp rates the interaction as minor. Penicillamine and Peramivir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are renally eliminated and penicillamine can be nephrotoxic. Reduced kidney function could raise peramivir exposure, though a direct pharmacokinetic interaction is not well established.
How serious is the interaction between Penicillamine and Peramivir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and adjust peramivir dosing according to creatinine clearance.
What other medicines interact with Penicillamine?
MediHelp also lists interactions of Penicillamine with, for example, Gold sodium thiomalate, Aluminum hydroxide, Calcium carbonate. The full list is on the Penicillamine page.
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