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Drug interactions

Prednisolone + Quercetin

Severity: Minor

Prednisolone and Quercetin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Quercetin is a flavonoid supplement that may affect P-glycoprotein, and any change in prednisolone exposure is theoretical. A clinically meaningful effect has not been well documented.

What this interaction means in plain words

Prednisolone and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible modulation of P-glycoprotein transport by quercetin, though the effect on prednisolone is not well established.

What to do

No routine action is needed; consider reviewing steroid response if high-dose quercetin supplements are started or stopped.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Prednisolone with Quercetin?

MediHelp rates the interaction as minor. Prednisolone and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quercetin is a flavonoid supplement that may affect P-glycoprotein, and any change in prednisolone exposure is theoretical. A clinically meaningful effect has not been well documented.

How serious is the interaction between Prednisolone and Quercetin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; consider reviewing steroid response if high-dose quercetin supplements are started or stopped.

What other medicines interact with Prednisolone?

MediHelp also lists interactions of Prednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Prednisolone page.

Full monographs, dosing and an interaction checker in the MediHelp app

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