Drug interactions
Prednisolone + Tick-borne encephalitis vaccine
Severity: Moderate
Prednisolone and Tick-borne encephalitis vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids may reduce the antibody response to inactivated tick-borne encephalitis vaccine, leaving less protection in endemic areas. The vaccine is not live.
What this interaction means in plain words
Prednisolone and Tick-borne encephalitis vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Glucocorticoid immunosuppression reduces vaccine-induced antibody production.
What to do
Complete the series before immunosuppression when possible. Consider checking antibody levels in patients on prolonged high-dose therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Prednisolone
- Bcg vaccine live + Prednisolone Contraindicated
- Measles mumps and rubella vaccine live + Prednisolone Contraindicated
- Measles mumps rubella and varicella vaccine live + Prednisolone Contraindicated
- Measles vaccine + Prednisolone Contraindicated
- Mifepristone + Prednisolone Contraindicated
- Prednisolone + Radium-223 dichloride Contraindicated
Frequently asked questions
Can I take Prednisolone with Tick-borne encephalitis vaccine?
MediHelp rates the interaction as moderate. Prednisolone and Tick-borne encephalitis vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticosteroids may reduce the antibody response to inactivated tick-borne encephalitis vaccine, leaving less protection in endemic areas. The vaccine is not live.
How serious is the interaction between Prednisolone and Tick-borne encephalitis vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete the series before immunosuppression when possible. Consider checking antibody levels in patients on prolonged high-dose therapy.
What other medicines interact with Prednisolone?
MediHelp also lists interactions of Prednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Prednisolone page.
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