Drug interactions
Promethazine + Terbutaline
Severity: Minor
Promethazine and Terbutaline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
There is no well-established interaction between these drugs. Terbutaline can cause tachycardia and tremor, and promethazine can cause sedation or tachycardia, but effects are not clearly additive.
What this interaction means in plain words
Promethazine and Terbutaline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Promethazine belongs to Respiratory; Terbutaline belongs to Respiratory.
Why it happens
No established mechanism; possible minor additive cardiovascular effects.
What to do
No specific action is needed. Monitor heart rate in patients with cardiac disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Promethazine
- Ibutilide + Promethazine Contraindicated
- Pimozide + Promethazine Contraindicated
- Promethazine + Thioridazine Contraindicated
- Alfentanil + Promethazine Major
- Amiodarone + Promethazine Major
- Amisulpride + Promethazine Major
Other interactions of Terbutaline
Frequently asked questions
Can I take Promethazine with Terbutaline?
MediHelp rates the interaction as minor. Promethazine and Terbutaline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. There is no well-established interaction between these drugs. Terbutaline can cause tachycardia and tremor, and promethazine can cause sedation or tachycardia, but effects are not clearly additive.
How serious is the interaction between Promethazine and Terbutaline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed. Monitor heart rate in patients with cardiac disease.
What other medicines interact with Promethazine?
MediHelp also lists interactions of Promethazine with, for example, Ibutilide, Pimozide, Thioridazine. The full list is on the Promethazine page.
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