Drug interactions
Pseudoephedrine + Terbutaline
Severity: Moderate
Pseudoephedrine and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs stimulate adrenergic pathways and can cause additive tachycardia, palpitations, tremor and hypertension. Patients with heart disease or hyperthyroidism are at greater risk.
What this interaction means in plain words
Pseudoephedrine and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pseudoephedrine belongs to Respiratory; Terbutaline belongs to Respiratory.
Why it happens
Additive adrenergic stimulation from beta-2 agonism and indirect sympathomimetic activity.
What to do
Monitor heart rate and blood pressure and avoid the combination in patients with significant cardiovascular disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Pseudoephedrine
- Isocarboxazid + Pseudoephedrine Contraindicated
- Phenelzine + Pseudoephedrine Contraindicated
- Pseudoephedrine + Rasagiline Contraindicated
- Pseudoephedrine + Selegiline Contraindicated
- Pseudoephedrine + Selegiline transdermal Contraindicated
- Pseudoephedrine + Tranylcypromine Contraindicated
Other interactions of Terbutaline
Frequently asked questions
Can I take Pseudoephedrine with Terbutaline?
MediHelp rates the interaction as moderate. Pseudoephedrine and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs stimulate adrenergic pathways and can cause additive tachycardia, palpitations, tremor and hypertension. Patients with heart disease or hyperthyroidism are at greater risk.
How serious is the interaction between Pseudoephedrine and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure and avoid the combination in patients with significant cardiovascular disease.
What other medicines interact with Pseudoephedrine?
MediHelp also lists interactions of Pseudoephedrine with, for example, Isocarboxazid, Phenelzine, Rasagiline. The full list is on the Pseudoephedrine page.
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