Drug interactions
Quinapril + Terazosin
Severity: Moderate
Quinapril and Terazosin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Adding an ACE inhibitor to an alpha-blocker lowers blood pressure more than either alone. First-dose hypotension and orthostatic symptoms are more likely when starting or increasing either drug.
What this interaction means in plain words
Quinapril and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypotensive effects of alpha-1 blockade and ACE inhibition.
What to do
Begin the added drug at a low dose, preferably at bedtime, and monitor standing blood pressure. Reduce the dose of either drug if symptomatic hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Frequently asked questions
Can I take Quinapril with Terazosin?
MediHelp rates the interaction as moderate. Quinapril and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Adding an ACE inhibitor to an alpha-blocker lowers blood pressure more than either alone. First-dose hypotension and orthostatic symptoms are more likely when starting or increasing either drug.
How serious is the interaction between Quinapril and Terazosin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Begin the added drug at a low dose, preferably at bedtime, and monitor standing blood pressure. Reduce the dose of either drug if symptomatic hypotension occurs.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
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