Drug interactions
Rapacuronium + Tolterodine
Severity: Minor
Rapacuronium and Tolterodine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rapacuronium is a neuromuscular blocker that was withdrawn from the market because of fatal bronchospasm. It has some muscarinic activity, but there is no established clinically relevant interaction with tolterodine.
What this interaction means in plain words
Rapacuronium and Tolterodine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No well-established mechanism; theoretical additive muscarinic blockade.
What to do
No specific action is required beyond routine perioperative monitoring.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolterodine
Frequently asked questions
Can I take Rapacuronium with Tolterodine?
MediHelp rates the interaction as minor. Rapacuronium and Tolterodine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rapacuronium is a neuromuscular blocker that was withdrawn from the market because of fatal bronchospasm. It has some muscarinic activity, but there is no established clinically relevant interaction with tolterodine.
How serious is the interaction between Rapacuronium and Tolterodine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is required beyond routine perioperative monitoring.
What other medicines interact with Tolterodine?
MediHelp also lists interactions of Tolterodine with, for example, Clarithromycin, Clozapine, Cobicistat. The full list is on the Tolterodine page.
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