Drug interactions
Reishi + Tolmetin
Severity: Minor
Reishi and Tolmetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reishi mushroom has reported antiplatelet activity, and tolmetin also inhibits platelet function and can injure the gastric lining. Bleeding risk may be modestly increased, although evidence is limited.
What this interaction means in plain words
Reishi and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive antiplatelet effects; the herbal mechanism is not well characterized.
What to do
Counsel patients to report easy bruising or bleeding and avoid adding the supplement if they also take anticoagulants.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Frequently asked questions
Can I take Reishi with Tolmetin?
MediHelp rates the interaction as minor. Reishi and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reishi mushroom has reported antiplatelet activity, and tolmetin also inhibits platelet function and can injure the gastric lining. Bleeding risk may be modestly increased, although evidence is limited.
How serious is the interaction between Reishi and Tolmetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to report easy bruising or bleeding and avoid adding the supplement if they also take anticoagulants.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
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