Drug interactions
Albuterol + Tranylcypromine
Severity: Moderate
Albuterol and Tranylcypromine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
MAO inhibitors may potentiate the cardiovascular effects of beta-agonists such as albuterol, causing tachycardia, palpitations and blood pressure changes. Inhaled use produces limited systemic exposure, so the effect is usually modest.
What this interaction means in plain words
Albuterol and Tranylcypromine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
MAO inhibition enhances the adrenergic and vascular effects of sympathomimetic agents.
What to do
Use the lowest effective albuterol dose and monitor heart rate and blood pressure. Consider alternatives if cardiovascular symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tranylcypromine
- 5-HTP + Tranylcypromine Contraindicated
- Amitriptyline + Tranylcypromine Contraindicated
- Amoxapine + Tranylcypromine Contraindicated
- Atomoxetine + Tranylcypromine Contraindicated
- Benzphetamine + Tranylcypromine Contraindicated
- Brimonidine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Albuterol with Tranylcypromine?
MediHelp rates the interaction as moderate. Albuterol and Tranylcypromine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. MAO inhibitors may potentiate the cardiovascular effects of beta-agonists such as albuterol, causing tachycardia, palpitations and blood pressure changes. Inhaled use produces limited systemic exposure, so the effect is usually modest.
How serious is the interaction between Albuterol and Tranylcypromine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective albuterol dose and monitor heart rate and blood pressure. Consider alternatives if cardiovascular symptoms occur.
What other medicines interact with Tranylcypromine?
MediHelp also lists interactions of Tranylcypromine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Tranylcypromine page.
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