Drug interactions
Albuterol + Vardenafil
Severity: Moderate
Albuterol and Vardenafil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vardenafil can prolong the QT interval and albuterol can cause hypokalemia and tachycardia, which may add to arrhythmic risk. The effect is mainly relevant with high-dose or nebulized albuterol or in patients with other risk factors.
What this interaction means in plain words
Albuterol and Vardenafil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT effects, with beta-agonist-induced hypokalemia and tachycardia increasing proarrhythmic susceptibility.
What to do
Monitor the ECG and serum potassium in patients with cardiac disease or other QT risk factors. Use the lowest effective albuterol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Vardenafil
- Amyl nitrite + Vardenafil Contraindicated
- Glyceryl trinitrate pr + Vardenafil Contraindicated
- Isosorbide dinitrate + Vardenafil Contraindicated
- Isosorbide mononitrate + Vardenafil Contraindicated
- Nicorandil + Vardenafil Contraindicated
- Nitroglycerin po + Vardenafil Contraindicated
Frequently asked questions
Can I take Albuterol with Vardenafil?
MediHelp rates the interaction as moderate. Albuterol and Vardenafil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vardenafil can prolong the QT interval and albuterol can cause hypokalemia and tachycardia, which may add to arrhythmic risk. The effect is mainly relevant with high-dose or nebulized albuterol or in patients with other risk factors.
How serious is the interaction between Albuterol and Vardenafil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor the ECG and serum potassium in patients with cardiac disease or other QT risk factors. Use the lowest effective albuterol dose.
What other medicines interact with Vardenafil?
MediHelp also lists interactions of Vardenafil with, for example, Amyl nitrite, Glyceryl trinitrate pr, Isosorbide dinitrate. The full list is on the Vardenafil page.
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