Drug interactions
Albuterol + Ziprasidone
Severity: Moderate
Albuterol and Ziprasidone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can prolong the QT interval, and albuterol can also cause hypokalemia and tachycardia, which increase the risk of torsades de pointes. The risk is higher with high-dose or nebulized albuterol and in patients with other risk factors.
What this interaction means in plain words
Albuterol and Ziprasidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QTc prolongation; beta-agonist-induced hypokalemia adds arrhythmic risk.
What to do
Check baseline ECG and electrolytes in patients with cardiac risk factors, and correct potassium and magnesium. Limit albuterol to the lowest effective dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ziprasidone
- Amiodarone + Ziprasidone Contraindicated
- Amitriptyline + Ziprasidone Contraindicated
- Arsenic trioxide + Ziprasidone Contraindicated
- Bedaquiline + Ziprasidone Contraindicated
- Chloroquine + Ziprasidone Contraindicated
- Citalopram + Ziprasidone Contraindicated
Frequently asked questions
Can I take Albuterol with Ziprasidone?
MediHelp rates the interaction as moderate. Albuterol and Ziprasidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can prolong the QT interval, and albuterol can also cause hypokalemia and tachycardia, which increase the risk of torsades de pointes. The risk is higher with high-dose or nebulized albuterol and in patients with other risk factors.
How serious is the interaction between Albuterol and Ziprasidone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes in patients with cardiac risk factors, and correct potassium and magnesium. Limit albuterol to the lowest effective dose.
What other medicines interact with Ziprasidone?
MediHelp also lists interactions of Ziprasidone with, for example, Amiodarone, Amitriptyline, Arsenic trioxide. The full list is on the Ziprasidone page.
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