Drug interactions
Salmeterol + Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol
Severity: Minor
Salmeterol and Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Salmeterol can lower serum potassium, and bowel preparations cause fluid and electrolyte losses. Together they may increase the risk of hypokalemia in susceptible patients, particularly those with cardiac disease.
What this interaction means in plain words
Salmeterol and Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive potassium lowering from beta-2-mediated intracellular shift and gastrointestinal electrolyte losses.
What to do
Maintain hydration and check electrolytes in patients with cardiac or renal disease or on other potassium-lowering drugs. Routine monitoring is otherwise unnecessary.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Salmeterol
- Ritonavir + Salmeterol Contraindicated
- Salmeterol + Saquinavir Contraindicated
- Amitriptyline + Salmeterol Major
- Arformoterol + Salmeterol Major
- Atazanavir + Salmeterol Major
- Budesonide-formoterol + Salmeterol Major
Frequently asked questions
Can I take Salmeterol with Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol?
MediHelp rates the interaction as minor. Salmeterol and Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Salmeterol can lower serum potassium, and bowel preparations cause fluid and electrolyte losses. Together they may increase the risk of hypokalemia in susceptible patients, particularly those with cardiac disease.
How serious is the interaction between Salmeterol and Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Maintain hydration and check electrolytes in patients with cardiac or renal disease or on other potassium-lowering drugs. Routine monitoring is otherwise unnecessary.
What other medicines interact with Salmeterol?
MediHelp also lists interactions of Salmeterol with, for example, Ritonavir, Saquinavir, Amitriptyline. The full list is on the Salmeterol page.
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