Drug interactions
Salsalate + Terazosin
Severity: Minor
Salsalate and Terazosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Salsalate is a weak inhibitor of prostaglandin synthesis, so any reduction in the antihypertensive effect of terazosin is expected to be small. Clinical relevance is limited.
What this interaction means in plain words
Salsalate and Terazosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic antagonism through minor inhibition of vasodilatory prostaglandins.
What to do
No dose change is usually needed; monitor blood pressure if terazosin is being used for hypertension and salsalate is used long term.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Frequently asked questions
Can I take Salsalate with Terazosin?
MediHelp rates the interaction as minor. Salsalate and Terazosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Salsalate is a weak inhibitor of prostaglandin synthesis, so any reduction in the antihypertensive effect of terazosin is expected to be small. Clinical relevance is limited.
How serious is the interaction between Salsalate and Terazosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; monitor blood pressure if terazosin is being used for hypertension and salsalate is used long term.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
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