Drug interactions
Shepherd's purse + Valsartan
Severity: Minor
Shepherd's purse and Valsartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Shepherd's purse has been reported to affect blood pressure and vascular tone, so it may unpredictably alter the antihypertensive response to valsartan. Evidence is theoretical.
What this interaction means in plain words
Shepherd's purse and Valsartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible pharmacodynamic opposition or variability of blood pressure effect; mechanism is not established.
What to do
Advise patients to avoid the herb where possible and check blood pressure if it is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Valsartan
- Aliskiren + Valsartan Contraindicated
- Sparsentan + Valsartan Contraindicated
- Aldesleukin + Valsartan Major
- Amifostine + Valsartan Major
- Amiloride + Valsartan Major
- Amlodipine-benazepril + Valsartan Major
Frequently asked questions
Can I take Shepherd's purse with Valsartan?
MediHelp rates the interaction as minor. Shepherd's purse and Valsartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shepherd's purse has been reported to affect blood pressure and vascular tone, so it may unpredictably alter the antihypertensive response to valsartan. Evidence is theoretical.
How serious is the interaction between Shepherd's purse and Valsartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid the herb where possible and check blood pressure if it is used.
What other medicines interact with Valsartan?
MediHelp also lists interactions of Valsartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Valsartan page.
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