Drug interactions
Sodium citrate / citric acid + Timolol
Severity: Minor
Sodium citrate / citric acid and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Citrate-based alkalinizing agents act as antacids and might slightly reduce the oral absorption of timolol. Evidence is sparse and the effect is expected to be small.
What this interaction means in plain words
Sodium citrate / citric acid and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Gastric pH changes may modestly reduce absorption of oral timolol.
What to do
Separate oral doses by about 2 hours and monitor heart rate and blood pressure.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Albuterol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
Frequently asked questions
Can I take Sodium citrate / citric acid with Timolol?
MediHelp rates the interaction as minor. Sodium citrate / citric acid and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Citrate-based alkalinizing agents act as antacids and might slightly reduce the oral absorption of timolol. Evidence is sparse and the effect is expected to be small.
How serious is the interaction between Sodium citrate / citric acid and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate oral doses by about 2 hours and monitor heart rate and blood pressure.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Albuterol, Aldesleukin. The full list is on the Timolol page.
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