Drug interactions
Somatrem + Triamcinolone
Severity: Moderate
Somatrem and Triamcinolone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucocorticoids at supraphysiologic doses can blunt the growth-promoting effects of growth hormone. Growth response may be reduced in children treated with both.
What this interaction means in plain words
Somatrem and Triamcinolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism of growth hormone effects by glucocorticoids, with growth hormone also inhibiting 11-beta-HSD-1.
What to do
Monitor growth velocity and use the lowest effective glucocorticoid dose. Adjust the growth hormone dose if response is inadequate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Triamcinolone
- Smallpox vaccine live + Triamcinolone Contraindicated
- Triamcinolone + Zoster vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Triamcinolone Major
- Aldesleukin + Triamcinolone Major
- Atazanavir + Triamcinolone Major
- Axicabtagene ciloleucel + Triamcinolone Major
Frequently asked questions
Can I take Somatrem with Triamcinolone?
MediHelp rates the interaction as moderate. Somatrem and Triamcinolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Glucocorticoids at supraphysiologic doses can blunt the growth-promoting effects of growth hormone. Growth response may be reduced in children treated with both.
How serious is the interaction between Somatrem and Triamcinolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor growth velocity and use the lowest effective glucocorticoid dose. Adjust the growth hormone dose if response is inadequate.
What other medicines interact with Triamcinolone?
MediHelp also lists interactions of Triamcinolone with, for example, Smallpox vaccine live, Zoster vaccine live, Adenovirus types 4 and 7 live. The full list is on the Triamcinolone page.
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