Drug interactions
Somatrogon + Theophylline
Severity: Minor
Somatrogon and Theophylline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Growth hormone products may raise CYP450-mediated drug clearance, potentially lowering theophylline concentrations. Evidence is limited and the effect is likely modest, but theophylline has a narrow therapeutic window.
What this interaction means in plain words
Somatrogon and Theophylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Somatrogon belongs to Endocrine; Theophylline belongs to Respiratory.
Why it happens
Growth hormone may induce CYP1A2 and CYP3A4, increasing theophylline metabolism.
What to do
Monitor clinical response and check theophylline levels if control worsens after somatrogon is started; adjust the dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Theophylline
- Riociguat + Theophylline Contraindicated
- Adenosine + Theophylline Major
- Apalutamide + Theophylline Major
- Bupropion + Theophylline Major
- Carvedilol + Theophylline Major
- Cimetidine + Theophylline Major
Other interactions of Somatrogon
- Alogliptin-metformin + Somatrogon Moderate
- Alogliptin-pioglitazone + Somatrogon Moderate
- Alogliptin + Somatrogon Moderate
- Canagliflozin-metformin + Somatrogon Moderate
- Chlorpropamide + Somatrogon Moderate
- Cyclosporin + Somatrogon Moderate
Frequently asked questions
Can I take Somatrogon with Theophylline?
MediHelp rates the interaction as minor. Somatrogon and Theophylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Growth hormone products may raise CYP450-mediated drug clearance, potentially lowering theophylline concentrations. Evidence is limited and the effect is likely modest, but theophylline has a narrow therapeutic window.
How serious is the interaction between Somatrogon and Theophylline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response and check theophylline levels if control worsens after somatrogon is started; adjust the dose if needed.
What other medicines interact with Theophylline?
MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.
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