Drug interactions
Streptozocin + Trastuzumab
Severity: Minor
Streptozocin and Trastuzumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Streptozocin is mainly nephrotoxic with less marrow suppression, but hematologic toxicity can occur. Combined with trastuzumab, additive cytopenias are possible.
What this interaction means in plain words
Streptozocin and Trastuzumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive myelosuppression.
What to do
Monitor blood counts and renal function during treatment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Trastuzumab
Frequently asked questions
Can I take Streptozocin with Trastuzumab?
MediHelp rates the interaction as minor. Streptozocin and Trastuzumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Streptozocin is mainly nephrotoxic with less marrow suppression, but hematologic toxicity can occur. Combined with trastuzumab, additive cytopenias are possible.
How serious is the interaction between Streptozocin and Trastuzumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and renal function during treatment.
What other medicines interact with Trastuzumab?
MediHelp also lists interactions of Trastuzumab with, for example, Daunorubicin, Doxorubicin liposomal, Doxorubicin. The full list is on the Trastuzumab page.
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