Drug interactions
Sulfamethoxazole + Telavancin
Severity: Moderate
Sulfamethoxazole and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents have been associated with QT prolongation, though the effect of sulfamethoxazole is weak and reported mainly in combination with trimethoprim. Together they may modestly increase arrhythmia risk in vulnerable patients.
What this interaction means in plain words
Sulfamethoxazole and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive QT prolongation.
What to do
Perform an ECG in patients with additional risk factors and correct electrolyte abnormalities. Monitor the QTc if combined therapy is needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Frequently asked questions
Can I take Sulfamethoxazole with Telavancin?
MediHelp rates the interaction as moderate. Sulfamethoxazole and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents have been associated with QT prolongation, though the effect of sulfamethoxazole is weak and reported mainly in combination with trimethoprim. Together they may modestly increase arrhythmia risk in vulnerable patients.
How serious is the interaction between Sulfamethoxazole and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Perform an ECG in patients with additional risk factors and correct electrolyte abnormalities. Monitor the QTc if combined therapy is needed.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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