Drug interactions
Telavancin + Umeclidinium bromide / vilanterol inhaled
Severity: Moderate
Telavancin and Umeclidinium bromide / vilanterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vilanterol, a long-acting beta agonist, can cause QT prolongation and tachycardia, particularly at higher systemic exposure. Telavancin may add a small further QT effect, though inhaled doses give low systemic exposure.
What this interaction means in plain words
Telavancin and Umeclidinium bromide / vilanterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta-agonist cardiovascular stimulation.
What to do
Monitor heart rhythm and QTc in patients with cardiac disease or electrolyte problems. Check potassium, as beta agonists can lower it.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Frequently asked questions
Can I take Telavancin with Umeclidinium bromide / vilanterol inhaled?
MediHelp rates the interaction as moderate. Telavancin and Umeclidinium bromide / vilanterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vilanterol, a long-acting beta agonist, can cause QT prolongation and tachycardia, particularly at higher systemic exposure. Telavancin may add a small further QT effect, though inhaled doses give low systemic exposure.
How serious is the interaction between Telavancin and Umeclidinium bromide / vilanterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rhythm and QTc in patients with cardiac disease or electrolyte problems. Check potassium, as beta agonists can lower it.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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