Drug interactions
Telavancin + Venlafaxine
Severity: Moderate
Telavancin and Venlafaxine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Venlafaxine has been associated with QT prolongation, mainly at high doses or in overdose, and telavancin may add to it. The combination may increase arrhythmia risk in predisposed patients.
What this interaction means in plain words
Telavancin and Venlafaxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Telavancin belongs to Anti Bacterial; Venlafaxine belongs to Central Nervous System.
Why it happens
Additive pharmacodynamic QTc prolongation.
What to do
Obtain a baseline ECG in patients with cardiac risk factors and monitor the QTc. Correct electrolyte abnormalities.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Venlafaxine
- Isocarboxazid + Venlafaxine Contraindicated
- Methylene blue + Venlafaxine Contraindicated
- Phenelzine + Venlafaxine Contraindicated
- Procarbazine + Venlafaxine Contraindicated
- Rasagiline + Venlafaxine Contraindicated
- Safinamide + Venlafaxine Contraindicated
Frequently asked questions
Can I take Telavancin with Venlafaxine?
MediHelp rates the interaction as moderate. Telavancin and Venlafaxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Venlafaxine has been associated with QT prolongation, mainly at high doses or in overdose, and telavancin may add to it. The combination may increase arrhythmia risk in predisposed patients.
How serious is the interaction between Telavancin and Venlafaxine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG in patients with cardiac risk factors and monitor the QTc. Correct electrolyte abnormalities.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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