Drug interactions
Teniposide + Trastuzumab
Severity: Moderate
Teniposide and Trastuzumab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teniposide causes severe myelosuppression. With trastuzumab, neutropenia and febrile neutropenia may be more frequent.
What this interaction means in plain words
Teniposide and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive myelosuppression.
What to do
Monitor complete blood counts and for fever or infection. Reduce or delay teniposide for severe neutropenia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Trastuzumab
Frequently asked questions
Can I take Teniposide with Trastuzumab?
MediHelp rates the interaction as moderate. Teniposide and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Teniposide causes severe myelosuppression. With trastuzumab, neutropenia and febrile neutropenia may be more frequent.
How serious is the interaction between Teniposide and Trastuzumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts and for fever or infection. Reduce or delay teniposide for severe neutropenia.
What other medicines interact with Trastuzumab?
MediHelp also lists interactions of Trastuzumab with, for example, Daunorubicin, Doxorubicin liposomal, Doxorubicin. The full list is on the Trastuzumab page.
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