Drug interactions
Tetanus toxoid adsorbed or fluid + Tocilizumab
Severity: Minor
Tetanus toxoid adsorbed or fluid and Tocilizumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetanus toxoid is non-live and can be given, but tocilizumab may somewhat reduce the antibody response. Studies of tocilizumab with tetanus toxoid have generally shown adequate responses.
What this interaction means in plain words
Tetanus toxoid adsorbed or fluid and Tocilizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
IL-6 receptor blockade may modestly dampen antibody production.
What to do
Give tetanus toxoid as clinically indicated, including wound management, without interrupting tocilizumab.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tocilizumab
- Bcg vaccine live + Tocilizumab Contraindicated
- Measles mumps and rubella vaccine live + Tocilizumab Contraindicated
- Measles mumps rubella and varicella vaccine live + Tocilizumab Contraindicated
- Measles vaccine + Tocilizumab Contraindicated
- Rubella vaccine + Tocilizumab Contraindicated
- Smallpox vaccine live + Tocilizumab Contraindicated
Frequently asked questions
Can I take Tetanus toxoid adsorbed or fluid with Tocilizumab?
MediHelp rates the interaction as minor. Tetanus toxoid adsorbed or fluid and Tocilizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tetanus toxoid is non-live and can be given, but tocilizumab may somewhat reduce the antibody response. Studies of tocilizumab with tetanus toxoid have generally shown adequate responses.
How serious is the interaction between Tetanus toxoid adsorbed or fluid and Tocilizumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give tetanus toxoid as clinically indicated, including wound management, without interrupting tocilizumab.
What other medicines interact with Tocilizumab?
MediHelp also lists interactions of Tocilizumab with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Tocilizumab page.
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