Drug interactions
Tetracycline + Ticarcillin
Severity: Moderate
Tetracycline and Ticarcillin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bacteriostatic tetracycline may reduce the bactericidal activity of ticarcillin, which depends on bacterial growth. This matters mainly in severe infections.
What this interaction means in plain words
Tetracycline and Ticarcillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism between a bacteriostatic agent and a growth-dependent bactericidal beta-lactam.
What to do
Avoid combining in infections requiring bactericidal therapy. If combined, monitor clinical response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tetracycline
- Acitretin + Tetracycline Contraindicated
- Methoxyflurane + Tetracycline Contraindicated
- Isotretinoin + Tetracycline Major
- Palovarotene + Tetracycline Major
- Strontium ranelate + Tetracycline Major
- Tetracycline + Tretinoin Major
Frequently asked questions
Can I take Tetracycline with Ticarcillin?
MediHelp rates the interaction as moderate. Tetracycline and Ticarcillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bacteriostatic tetracycline may reduce the bactericidal activity of ticarcillin, which depends on bacterial growth. This matters mainly in severe infections.
How serious is the interaction between Tetracycline and Ticarcillin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining in infections requiring bactericidal therapy. If combined, monitor clinical response.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Methoxyflurane, Isotretinoin. The full list is on the Tetracycline page.
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