Drug interactions
Tetracycline + Tripotassium dicitratobismuthate
Severity: Minor
Tetracycline and Tripotassium dicitratobismuthate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bismuth salts bind tetracycline in the gut and reduce its absorption. In bismuth quadruple Helicobacter pylori regimens, tetracycline is deliberately combined with bismuth and the regimen is established.
What this interaction means in plain words
Tetracycline and Tripotassium dicitratobismuthate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Chelation or complexation of tetracycline by bismuth in the gastrointestinal tract.
What to do
No change is needed when using a standard bismuth quadruple regimen. Otherwise separate other doses by about 2 hours.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tetracycline
- Acitretin + Tetracycline Contraindicated
- Methoxyflurane + Tetracycline Contraindicated
- Isotretinoin + Tetracycline Major
- Palovarotene + Tetracycline Major
- Strontium ranelate + Tetracycline Major
- Tetracycline + Tretinoin Major
Frequently asked questions
Can I take Tetracycline with Tripotassium dicitratobismuthate?
MediHelp rates the interaction as minor. Tetracycline and Tripotassium dicitratobismuthate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bismuth salts bind tetracycline in the gut and reduce its absorption. In bismuth quadruple Helicobacter pylori regimens, tetracycline is deliberately combined with bismuth and the regimen is established.
How serious is the interaction between Tetracycline and Tripotassium dicitratobismuthate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is needed when using a standard bismuth quadruple regimen. Otherwise separate other doses by about 2 hours.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Methoxyflurane, Isotretinoin. The full list is on the Tetracycline page.
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