Drug interactions
Tick-borne encephalitis vaccine + Tocilizumab
Severity: Moderate
Tick-borne encephalitis vaccine and Tocilizumab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tocilizumab may reduce the antibody response to inactivated tick-borne encephalitis vaccine. Protection may be incomplete in patients living in or travelling to endemic areas.
What this interaction means in plain words
Tick-borne encephalitis vaccine and Tocilizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
IL-6 receptor blockade attenuates humoral responses to vaccination.
What to do
Complete the primary series before tocilizumab when possible; otherwise vaccinate and consider checking antibody titres.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tocilizumab
- Bcg vaccine live + Tocilizumab Contraindicated
- Measles mumps and rubella vaccine live + Tocilizumab Contraindicated
- Measles mumps rubella and varicella vaccine live + Tocilizumab Contraindicated
- Measles vaccine + Tocilizumab Contraindicated
- Rubella vaccine + Tocilizumab Contraindicated
- Smallpox vaccine live + Tocilizumab Contraindicated
Frequently asked questions
Can I take Tick-borne encephalitis vaccine with Tocilizumab?
MediHelp rates the interaction as moderate. Tick-borne encephalitis vaccine and Tocilizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tocilizumab may reduce the antibody response to inactivated tick-borne encephalitis vaccine. Protection may be incomplete in patients living in or travelling to endemic areas.
How serious is the interaction between Tick-borne encephalitis vaccine and Tocilizumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete the primary series before tocilizumab when possible; otherwise vaccinate and consider checking antibody titres.
What other medicines interact with Tocilizumab?
MediHelp also lists interactions of Tocilizumab with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Tocilizumab page.
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