Drug interactions
Tocilizumab + Travelers diarrhea and cholera vaccine inactivated
Severity: Minor
Tocilizumab and Travelers diarrhea and cholera vaccine inactivated: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tocilizumab may reduce the immune response to this inactivated oral vaccine. No replication risk exists, but protective efficacy may be lower.
What this interaction means in plain words
Tocilizumab and Travelers diarrhea and cholera vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
IL-6 receptor blockade may reduce antibody responses to vaccine antigens.
What to do
Vaccinate as indicated and reinforce food and water precautions for travellers on tocilizumab.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tocilizumab
- Bcg vaccine live + Tocilizumab Contraindicated
- Measles mumps and rubella vaccine live + Tocilizumab Contraindicated
- Measles mumps rubella and varicella vaccine live + Tocilizumab Contraindicated
- Measles vaccine + Tocilizumab Contraindicated
- Rubella vaccine + Tocilizumab Contraindicated
- Smallpox vaccine live + Tocilizumab Contraindicated
Frequently asked questions
Can I take Tocilizumab with Travelers diarrhea and cholera vaccine inactivated?
MediHelp rates the interaction as minor. Tocilizumab and Travelers diarrhea and cholera vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tocilizumab may reduce the immune response to this inactivated oral vaccine. No replication risk exists, but protective efficacy may be lower.
How serious is the interaction between Tocilizumab and Travelers diarrhea and cholera vaccine inactivated?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate as indicated and reinforce food and water precautions for travellers on tocilizumab.
What other medicines interact with Tocilizumab?
MediHelp also lists interactions of Tocilizumab with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Tocilizumab page.
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