Flibanserin

موارد مصرف

• Hypoactive sexual desire disorder

نحوه اثر

دوز معمول بزرگسالان (خلاصه برچسب)

خلاصه برچسب فقط برای نخستین سطر دوزبندی؛ بخش‌های کامل دوزبندی در اپلیکیشن موجود است.

بارداری و شیردهی

بارداری

Unknown No studies in pregnant women. In rats and rabbits, fetal harm occurred only at more than 15 times human exposure with maternal toxicity. It is for premenopausal women with low sexual desire; stop if pregnancy occurs.

شیردهی

Unsafe Not known whether it passes into human milk; it does into rat milk. LactMed: high protein binding suggests low milk levels. US label: not recommended while breastfeeding because of possible serious effects, including sedation, in the infant.

عوارض جانبی گزارش‌شده

• Fatigue
• Nausea
• Insomnia
• Somnolence
• Dizziness

موارد منع مصرف

• Coadministration with moderate or strong CYP3A4 inhibitors
• Hepatic impairment
• Known hypersensitivity to drug or excipients

چه کسانی باید احتیاط کنند

• Coadministration with moderate or strong CYP3A4 inhibitors increases flibanserin concentrations, which can cause severe hypotension and syncope.
• Hypersensitivity reactions, including anaphylaxis, reactions consistent with angioedema (eg, swelling of the face, lips, and mouth), pruritus, and urticaria reported.
• Flibanserin may increase blood concentrations of P-gp substrates (eg, digoxin, sirolimus).

بارداری یا شیردهی، بیماری کلیه یا کبد، آلرژی‌ها و هر داروی یا مکمل دیگری را که مصرف می‌کنید به داروساز یا پزشک خود اطلاع دهید.

مهم‌ترین تداخلات (278)

• Atazanavir + Flibanserin Contraindicated
• Ceritinib + Flibanserin Contraindicated
• Clarithromycin + Flibanserin Contraindicated
• Cobicistat + Flibanserin Contraindicated
• Conivaptan + Flibanserin Contraindicated
• Crizotinib + Flibanserin Contraindicated
• Cyclosporin + Flibanserin Contraindicated
• Cyclosporine + Flibanserin Contraindicated
• Darunavir + Flibanserin Contraindicated
• Diltiazem + Flibanserin Contraindicated

All 278 interactions, with severity and what to do

پرسش‌های متداول