Drug reference
flibanserin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Genitourinary (Female Viagra)
Mechanism of action
Postsynaptic serotonin-1A (5HT-1A) receptor agonist and 5HT-2A receptor antagonist; also elicits moderate antagonist activities at the 5-HT2B, 5-HT2C, and dopamine D4 receptors.
Common side effects
- Insomnia
- Dizziness
- Somnolence
- Fatigue
- Nausea
Contraindications
- Coadministration with moderate or strong CYP3A4 inhibitors Hepatic impairment Known hypersensitivity to drug or excipients
Known interactions (30)
- clarithromycin + flibanserin Contraindicated
- crizotinib + flibanserin Contraindicated
- cyclosporin + flibanserin Contraindicated
- diltiazem + flibanserin Contraindicated
- dronedarone + flibanserin Contraindicated
- erythromycin + flibanserin Contraindicated
- flibanserin + fluconazole Contraindicated
- flibanserin + itraconazole Contraindicated
- flibanserin + ketoconazole Contraindicated
- flibanserin + netupitant-palonosetron Contraindicated
- flibanserin + posaconazole Contraindicated
- flibanserin + ribociclib Contraindicated
- flibanserin + verapamil Contraindicated
- flibanserin + voriconazole Contraindicated
- amiodarone + flibanserin Major
- aprepitant + flibanserin Major
- ciprofloxacin + flibanserin Major
- flibanserin + imatinib Major
- flibanserin + lapatinib Major
- flibanserin + nicardipine Major
- bicalutamide + flibanserin Moderate
- colchicine + flibanserin Moderate
- doxycycline + flibanserin Moderate
- flibanserin + haloperidol Moderate
- flibanserin + isoniazid Moderate
- flibanserin + metronidazole Moderate
- flibanserin + quinidine Moderate
- flibanserin + sertraline Moderate
- flibanserin + ticagrelor Moderate
- flibanserin + zileuton Moderate
Related conditions
Frequently asked questions
What drug class is flibanserin?
flibanserin belongs to: Genitourinary.
How does flibanserin work?
Postsynaptic serotonin-1A (5HT-1A) receptor agonist and 5HT-2A receptor antagonist; also elicits moderate antagonist activities at the 5-HT2B, 5-HT2C, and dopamine D4 receptors.
What are the common side effects of flibanserin?
Insomnia, Dizziness, Somnolence, Fatigue, Nausea
Which drugs interact with flibanserin?
clarithromycin, crizotinib, cyclosporin, diltiazem, dronedarone, erythromycin, fluconazole, itraconazole, ketoconazole, netupitant-palonosetron, posaconazole, ribociclib, verapamil, voriconazole, amiodarone
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