تداخل‌های دارویی
Abrocitinib + Ticagrelor
شدت: شدید
Abrocitinib and Ticagrelor: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Abrocitinib reduces platelet counts, mainly in the early weeks of treatment, and its labeling advises against antiplatelet drugs other than low-dose aspirin during the first 3 months. Adding ticagrelor, a potent P2Y12 inhibitor, to thrombocytopenia increases the risk of significant bleeding.
معنای این تداخل به زبان ساده
Abrocitinib and Ticagrelor can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Abrocitinib belongs to Miscellaneous; Ticagrelor belongs to Cardiovascular.
چرا رخ می‌دهد
Additive bleeding risk from ticagrelor platelet inhibition combined with abrocitinib-associated reduction in platelet count.
اقدام لازم
Avoid starting abrocitinib in patients who need ticagrelor during the first 3 months, or choose an alternative therapy. If unavoidable, monitor platelet counts and bleeding signs closely.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Abrocitinib و Ticagrelor، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Ticagrelor
- Itraconazole + Ticagrelor منع مصرف
- Ketoconazole + Ticagrelor منع مصرف
- Levoketoconazole + Ticagrelor منع مصرف
- Abciximab + Ticagrelor شدید
- Acalabrutinib + Ticagrelor شدید
- Acetylsalicylic acid + Ticagrelor شدید
تداخلات دیگر Abrocitinib
پرسش‌های متداول
Can I take Abrocitinib with Ticagrelor?
MediHelp rates the interaction as major. Abrocitinib and Ticagrelor can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Abrocitinib reduces platelet counts, mainly in the early weeks of treatment, and its labeling advises against antiplatelet drugs other than low-dose aspirin during the first 3 months. Adding ticagrelor, a potent P2Y12 inhibitor, to thrombocytopenia increases the risk of significant bleeding.
How serious is the interaction between Abrocitinib and Ticagrelor?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid starting abrocitinib in patients who need ticagrelor during the first 3 months, or choose an alternative therapy. If unavoidable, monitor platelet counts and bleeding signs closely.
What other medicines interact with Ticagrelor?
MediHelp also lists interactions of Ticagrelor with, for example, Itraconazole, Ketoconazole, Levoketoconazole. The full list is on the Ticagrelor page.
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