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Acetylsalicylic acid + Ticagrelor

شدت: شدید

Acetylsalicylic acid and Ticagrelor: major interaction.

آخرین به‌روزرسانی

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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Maintenance aspirin doses above 100 mg daily reduce the clinical benefit of ticagrelor, with worse cardiovascular outcomes seen. The combination is standard with low-dose aspirin, but bleeding risk is additive.

معنای این تداخل به زبان ساده

Acetylsalicylic acid and Ticagrelor can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Acetylsalicylic acid belongs to Musculoskeletal; Ticagrelor belongs to Cardiovascular.

سطح شواهد: High

چرا رخ می‌دهد

Additive platelet inhibition increases bleeding, and higher aspirin doses appear to diminish ticagrelor efficacy through a mechanism that is not fully understood.

اقدام لازم

Keep maintenance aspirin at 75-100 mg daily after any initial loading dose. Monitor for bleeding.

از داروساز چه بپرسید

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Acetylsalicylic acid و Ticagrelor، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Acetylsalicylic acid with Ticagrelor?

MediHelp rates the interaction as major. Acetylsalicylic acid and Ticagrelor can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Maintenance aspirin doses above 100 mg daily reduce the clinical benefit of ticagrelor, with worse cardiovascular outcomes seen. The combination is standard with low-dose aspirin, but bleeding risk is additive.

How serious is the interaction between Acetylsalicylic acid and Ticagrelor?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Keep maintenance aspirin at 75-100 mg daily after any initial loading dose. Monitor for bleeding.

What other medicines interact with Acetylsalicylic acid?

MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.

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