تداخلهای دارویی
Acemetacin + Mesalamine
شدت: متوسط
Acemetacin and Mesalamine: moderate interaction.
آخرین بهروزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصهای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمیشود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Mesalamine can rarely cause interstitial nephritis and NSAIDs such as acemetacin impair renal prostaglandin-dependent perfusion. Together they may increase the risk of kidney injury, especially with dehydration or existing renal disease.
معنای این تداخل به زبان ساده
Acemetacin and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
چرا رخ میدهد
Additive nephrotoxicity through NSAID-mediated renal hemodynamic effects and mesalamine-related interstitial nephritis.
اقدام لازم
Monitor serum creatinine and urine output at baseline and periodically. Avoid combining in patients with renal impairment.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیههای کامل مدیریت Acemetacin و Mesalamine، یادداشتهای تکمیلی، جزئیات شواهد و بررسیکننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Mesalamine
پرسشهای متداول
Can I take Acemetacin with Mesalamine?
MediHelp rates the interaction as moderate. Acemetacin and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mesalamine can rarely cause interstitial nephritis and NSAIDs such as acemetacin impair renal prostaglandin-dependent perfusion. Together they may increase the risk of kidney injury, especially with dehydration or existing renal disease.
How serious is the interaction between Acemetacin and Mesalamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output at baseline and periodically. Avoid combining in patients with renal impairment.
What other medicines interact with Mesalamine?
MediHelp also lists interactions of Mesalamine with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Mesalamine page.
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مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.