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Acetylsalicylic acid + Mesalamine

شدت: متوسط

Acetylsalicylic acid and Mesalamine: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Mesalamine is a salicylate with potential for renal toxicity, and combining it with aspirin or other NSAIDs may add to the risk of kidney injury. The risk is mainly with higher aspirin doses or pre-existing renal impairment.

معنای این تداخل به زبان ساده

Acetylsalicylic acid and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Acetylsalicylic acid belongs to Musculoskeletal; Mesalamine belongs to Gastrointestinal Tract.

سطح شواهد: Low

چرا رخ می‌دهد

Additive effects on renal prostaglandin-dependent perfusion and possible direct tubulointerstitial toxicity of salicylates.

اقدام لازم

Monitor serum creatinine and urinalysis periodically, particularly with higher-dose aspirin or renal impairment. Avoid unnecessary additional NSAIDs.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Acetylsalicylic acid و Mesalamine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Acetylsalicylic acid with Mesalamine?

MediHelp rates the interaction as moderate. Acetylsalicylic acid and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mesalamine is a salicylate with potential for renal toxicity, and combining it with aspirin or other NSAIDs may add to the risk of kidney injury. The risk is mainly with higher aspirin doses or pre-existing renal impairment.

How serious is the interaction between Acetylsalicylic acid and Mesalamine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urinalysis periodically, particularly with higher-dose aspirin or renal impairment. Avoid unnecessary additional NSAIDs.

What other medicines interact with Acetylsalicylic acid?

MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.

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