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Acetylsalicylic acid + Hydrocortisone

شدت: متوسط

Acetylsalicylic acid and Hydrocortisone: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Systemic corticosteroids combined with aspirin increase the risk of gastric ulceration and gastrointestinal bleeding. Corticosteroids may also lower salicylate levels, which can rise when the steroid is withdrawn.

معنای این تداخل به زبان ساده

Acetylsalicylic acid and Hydrocortisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Acetylsalicylic acid belongs to Musculoskeletal; Hydrocortisone belongs to Endocrine.

سطح شواهد: Moderate

چرا رخ می‌دهد

Additive gastric mucosal injury, plus corticosteroid-induced increase in salicylate clearance.

اقدام لازم

Consider a proton pump inhibitor in patients with ulcer risk factors. Monitor for GI bleeding and for salicylate toxicity when steroids are tapered at high aspirin doses.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Acetylsalicylic acid و Hydrocortisone، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Acetylsalicylic acid with Hydrocortisone?

MediHelp rates the interaction as moderate. Acetylsalicylic acid and Hydrocortisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids combined with aspirin increase the risk of gastric ulceration and gastrointestinal bleeding. Corticosteroids may also lower salicylate levels, which can rise when the steroid is withdrawn.

How serious is the interaction between Acetylsalicylic acid and Hydrocortisone?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider a proton pump inhibitor in patients with ulcer risk factors. Monitor for GI bleeding and for salicylate toxicity when steroids are tapered at high aspirin doses.

What other medicines interact with Acetylsalicylic acid?

MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.

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